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Properties of herbal extracts against Propionibacterium acnes for biomedical application
- Authors
- Lim Y.-M.; Kim S.E.; Kim Y.S.; Shin Y.M.; Jeong S.I.; Jo S.-Y.; Gwon H.-J.; Park J.-S.; Nho Y.-C.; Kim J.-C.; Kim S.-J.; Shin H.
- Issue Date
- Oct-2012
- Publisher
- SPIE-INT SOC OPTICAL ENGINEERING
- Keywords
- anti-bacterial; anti-inflammatory; Propionibacterium acnes
- Citation
- Progress in Biomedical Optics and Imaging - Proceedings of SPIE, v.8548
- Indexed
- SCOPUS
- Journal Title
- Progress in Biomedical Optics and Imaging - Proceedings of SPIE
- Volume
- 8548
- ISSN
- 1605-7422
1996-756X
- Abstract
- Propionibacterium acnes (P. acnes), one of the anaerobic bacterium, causes inflammatory acne. To find a novel medication for treating the inflammation caused by P. acnes, we investigated the anti-bacterial and anti-inflammatory activities of several herbal extracts against P. acnes. The aqueous extracts from five dried herbs, Phellodendron amurense Rupr., Paeonia lactiflora Pallas., Houttuynia cordata Thunb., Agrimonia pilosa Ledeb. and Glycyrrhiza uralensis Fisch., were prepared and mixed. In this experiment, 1 mg/ml of the herbal extract mixture caused a decrease in the growth of P. acnes and reduced the production of pro-inflammatory cytokines, TNF-α, IL-8, IL-1β and IL-6, in human monocytic THP-1 cells treated with heat-killed P. acnes. Therefore, this herbal extract mixture may possess both anti-bacterial and anti-inflammatory activities against P. acnes and can be a novel therapeutic agent for treating inflammatory acne. © 2012 SPIE.
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Collections - 4. Research institute > Nano-based Disease Control Institute > 1. Journal Articles
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Related Researcher
- Kim, Sung Eun
- Research Institute (Nano-based Disease Control Institute)