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Spinal cord injury after conducting transcatheter arterial chemoembolization for costal metastasis of hepatocellular carcinoma

Authors
Park S.J.Kim C.H.Kim J.D.Um S.H.Yim S.Y.Seo M.H.Lee D.I.Kang J.H.Keum B.Kim Y.S.
Issue Date
Sep-2012
Keywords
Hepatocellular carcinoma; TACE; Costal metastasis; Paraplegia
Citation
Clinical and molecular hepatology, v.18, no.3, pp.316 - 320
Indexed
SCOPUS
KCI
Journal Title
Clinical and molecular hepatology
Volume
18
Number
3
Start Page
316
End Page
320
URI
https://scholarworks.korea.ac.kr/kumedicine/handle/2020.sw.kumedicine/43629
DOI
10.3350/cmh.2012.18.3.316
ISSN
2287-285X
Abstract
Transcatheter arterial chemoembolization (TACE) has been used widely to treat patients with unresectable hepatocellular carcinoma. However, this method can induce various adverse events caused by necrosis of the tumor itself or damage to nontumor tissues. In particular, neurologic side effects such as cerebral infarction and paraplegia, although rare, may cause severe sequelae and permanent disability. Detailed information regarding the treatment process and prognosis associated with this procedure is not yet available. We experienced a case of paraplegia that occurred after conducting TACE through the intercostal artery to treat hepatocellular carcinoma that had metastasized to the rib. In this case, TACE was attempted to relieve severe bone pain, which had persisted even after palliative radiotherapy. A sudden impairment of sensory and motor functions after TACE developed in the trunk below the level of the sternum and in both lower extremities. The patient subsequently received steroid pulse therapy along with supportive care and continuous rehabilitation. At the time of discharge the patient had recovered sufficiently to enable him to walk by himself, although some paresthesia and spasticity remained.
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2. Clinical Science > Department of Pathology > 1. Journal Articles
2. Clinical Science > Department of Gastroenterology and Hepatology > 1. Journal Articles

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Yim, Sun Young
Anam Hospital (Department of Gastroenterology and Hepatology, Anam Hospital)
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