Successful treatment of disseminated interdigitating dendritic cell sarcoma with adriamycin, bleomycin, vinblastine, and dacarbazine chemotherapy
- Authors
- Lee S.-Y.; Lee S.R.; Chang W.J.; Kim H.S.; Kim B.S.; Kim I.S.
- Issue Date
- Jun-2012
- Keywords
- ABVD chemotherapy; Complete remission; IDCS
- Citation
- Korean Journal of Hematology, v.47, no.2, pp 150 - 153
- Pages
- 4
- Indexed
- SCOPUS
KCI
- Journal Title
- Korean Journal of Hematology
- Volume
- 47
- Number
- 2
- Start Page
- 150
- End Page
- 153
- URI
- https://scholarworks.korea.ac.kr/kumedicine/handle/2020.sw.kumedicine/43649
- DOI
- 10.5045/kjh.2012.47.2.150
- ISSN
- 1738-7949
- Abstract
- Interdigitating dendritic cell sarcoma (IDCS) is a very rare and aggressive neoplasm that arises from antigen presenting cells. IDCS usually involves lymph nodes; however, extra- nodal involvement has also been reported. Because a consistent standard therapy for IDCS has not been established to date, we report a case of the successful treatment of disseminated IDCS using ABVD chemotherapy (doxorubicin, bleomycin, vinblastine, and dacarbazine). A 64-year-old man was diagnosed with IDCS on the basis of immunohistochemical findings of a biopsy specimen of the inferior nasal concha. Immunohistochemical staining showed a positive reaction for CD68, leukocyte common antigen, and S-100 protein, but a negative reaction for CD34, CD1a, and CD21. Imaging studies showed cervical and axillary lymphadenopathies, subcutaneous nodules, and a soft tissue lesion in the nasal cavity. Treatment with the ABVD regimen resulted in complete remission after 8 cycles of chemotherapy. © 2012 Korean Society of Hematology.
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- Appears in
Collections - 1. Basic Science > Department of Pathology > 1. Journal Articles
- 2. Clinical Science > Department of Medical Oncology and Hematology > 1. Journal Articles
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