Physical Activity Frequency and the Risk of Stroke: A Nationwide Cohort Study in Korea
- Authors
- Jeong, Han-Gil; Kim, Do Yeon; Kang, Dong-Wan; Kim, Beom Joon; Kim, Chi Kyung; Kim, Yerim; Yang, Wookjin; Park, Eun-Sun; Lee, Seung-Hoon
- Issue Date
- Sep-2017
- Publisher
- WILEY
- Keywords
- physical activity; primary prevention; risk factor; stroke
- Citation
- JOURNAL OF THE AMERICAN HEART ASSOCIATION, v.6, no.9
- Indexed
- SCIE
SCOPUS
- Journal Title
- JOURNAL OF THE AMERICAN HEART ASSOCIATION
- Volume
- 6
- Number
- 9
- URI
- https://scholarworks.korea.ac.kr/kumedicine/handle/2020.sw.kumedicine/4666
- DOI
- 10.1161/JAHA.117.005671
- ISSN
- 2047-9980
- Abstract
- Background-The current guideline recommends moderate-to vigorous-intensity physical activity (PA) at least 40 min/day for 3 to 4 days/week. Although recent evidence has demonstrated that low-dose PA could reduce cardiovascular mortality, the relationship between low-dose PA and the risk of stroke remains uncertain. Methods and Results-Using data from a nation-wide sample cohort in Korea, we examined 336 326 individuals who received a general health examination between 2009 and 2010. Level of PA was assessed using a questionnaire for weekly PA frequencies regarding 3 intensity categories: light, moderate, and vigorous. Moderate-to vigorous-intensity PA (MVPA) was classified into 4 frequency categories: none, 1 to 2, 3 to 4, or >= 5 times/week. Cox proportional hazard models were constructed to estimate the risk of stroke. During the average follow-up of 3.6 years, 2213 stroke cases occurred. MVPA was none in 50%, 1 to 2 times/week in 20%, 3 to 4 times/week in 13%, and >= 5 times/week in 18% of the cohort. Individuals with MVPA 1 to 2 times/week had a 16% reduced risk of stroke (adjusted hazard ratio, 0.84; 95% confidence interval, 0.73-0.96) compared with those with no MVPA. The population attributable fraction of no MVPA was 12%, which was the second most important risk factor for a stroke after hypertension. Conclusions-Even 1 to 2 times a week of MVPA might be beneficial to prevent a first-ever stroke in the general population, although a quantitative validation of the questionnaire is needed. From a public health perspective, we need to encourage inactive people to start exercising with more-achievable goals.
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Collections - 2. Clinical Science > Department of Neurology > 1. Journal Articles
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