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Use of hepatobiliary phase images in Gd-EOB-DTPA-enhanced MRI of breast cancer hepatic metastasis to predict response to chemotherapy
- Issue Date
- May-2017
- Publisher
- ELSEVIER SCIENCE INC
- Keywords
- Gadoxetic acid; MRI; Hepatobiliary phase (HBP); Breast cancer liver metastases; Chemotherapy response
- Citation
- CLINICAL IMAGING, v.43, pp 127 - 131
- Pages
- 5
- Indexed
- SCIE
SCOPUS
- Journal Title
- CLINICAL IMAGING
- Volume
- 43
- Start Page
- 127
- End Page
- 131
- ISSN
- 0899-7071
1873-4499
- Abstract
- Objectives: To determine the prognostic value of Gd-EOB-DTPA MRI findings of liver metastasis from breast cancer. Methods: 29 metastatic lesions from 12 breast cancer patients who received chemotherapy were retrospectively reviewed. We evaluated hepatobiliary phase of the lesions and classified them as a "target" or "non-target" appearance. The relationship of appearance or SI ratio with tumor response was analyzed. Results: A non-target appearance was more frequent in disease control group than in non-control group [14/18 (77.8%) vs. 4/18 (222%)], and it was associated with a better response [p = 0.048]. Conclusion: HBP analysis may be useful to predict the response to chemotherapy and survival. (C) 2017 Elsevier Inc. All rights reserved.
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Collections - 2. Clinical Science > Department of Radiology > 1. Journal Articles
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Related Researcher
- Lee, Chang Hee
- Guro Hospital (Department of Radiology, Guro Hospital)