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A Case of Vanishing Bile Duct Syndrome after Drug-Induced Liver Injury Caused by Pelubiprofen
- Issue Date
- Dec-2020
- Publisher
- 연세대학교의과대학
- Keywords
- Pelubiprofen; vanishing bile duct syndrome; bile duct disease; drug-induced liver
- Citation
- Yonsei Medical Journal, v.61, no.12, pp 1060 - 1063
- Pages
- 4
- Indexed
- SCIE
SCOPUS
KCI
- Journal Title
- Yonsei Medical Journal
- Volume
- 61
- Number
- 12
- Start Page
- 1060
- End Page
- 1063
- ISSN
- 0513-5796
1976-2437
- Abstract
- Vanishing bile duct syndrome (VBDS) is a rare disease characterized by ductopenia and cholestasis, and is linked to immunological damage to the bile duct system. VBDS can be triggered by infection, ischemia, autoimmune diseases, adverse drug reactions, and humoral factors associated with malignancy. A few cases of VBDS associated with nonsteroidal anti-inflammatory drug-related drug-induced liver injury (DILI) have been reported. Here, we report a case of a 29-year-old patient who developed DILI that progressed to VBDS after the administration of pelubiprofen.
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Related Researcher
- Lee, Young Sun
- Guro Hospital (Department of Gastroenterology and Hepatology, Guro Hospital)