Perinatal Outcomes Associated with Latency in Late Preterm Premature Rupture of Membranes
- Authors
- Choi, Eui Kyung; Kim, So Yeon; Heo, Ji-Man; Park, Kyu Hee; Kim, Ho Yeon; Choi, Byung Min; Kim, Hai-Joong
- Issue Date
- Jan-2021
- Publisher
- Multidisciplinary Digital Publishing Institute (MDPI)
- Keywords
- preterm premature rupture of membranes 1; late preterm 2; preterm birth 3; expectant management 4; antenatal corticosteroids 5; neonatal sepsis 6; respiratory distress syndrome 7
- Citation
- International Journal of Environmental Research and Public Health, v.18, no.2, pp 1 - 9
- Pages
- 9
- Indexed
- SCIE
SSCI
SCOPUS
- Journal Title
- International Journal of Environmental Research and Public Health
- Volume
- 18
- Number
- 2
- Start Page
- 1
- End Page
- 9
- URI
- https://scholarworks.korea.ac.kr/kumedicine/handle/2020.sw.kumedicine/51940
- DOI
- 10.3390/ijerph18020672
- ISSN
- 1661-7827
1660-4601
- Abstract
- This study aims to evaluate the perinatal outcomes of preterm premature rupture of membrane (PPROM) with latency periods at 33 + 0-36 + 6 weeks of gestation. This retrospective case-control study included women with singleton pregnancies who delivered at 33 + 0-36 + 6 weeks at Korea University Ansan Hospital in South Korea between 2006-2019. The maternal and neonatal characteristics were compared between different latency periods (expectant delivery >= 72 h vs. immediate delivery <72 h). Data were compared among 345 women (expectant, n = 39; immediate delivery, n = 306). There was no significant difference in maternal and neonatal morbidities between the groups, despite the younger gestational age in the expectant delivery group. Stratified by gestational weeks, the 34-week infants showed a statistically significant lower exposure to antenatal steroids (73.4% vs. 20.0%, p < 0.001), while the incidence of respiratory distress syndrome (12.8%) and the use of any respiratory support (36.8%) was higher than those in the 33-week infants, without significance. Our study shows that a prolonged latency period (>= 72 h) did not increase maternal and neonatal morbidities, and a considerable number of preterm infants immediately delivered at 34 weeks experienced respiratory complications. Expectant management and antenatal corticosteroids should be considered in late preterm infants with PPROM.
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- Appears in
Collections - 2. Clinical Science > Department of Obstetrics and Gynecology > 1. Journal Articles
- 2. Clinical Science > Department of Pediatrics > 1. Journal Articles
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