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Cited 2 time in webofscience Cited 3 time in scopus
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Better health-related quality of life in kidney transplant patients compared to chronic kidney disease patients with similar renal function

Authors
Ryu, Jung-HwaKoo, Tai YeonRo, HanCho, Jang-HeeKim, Myung-GyuHa Huh, KyuPark, Jae BermLee, SikHan, SeungyeupKim, JayounOh, Kook-HwanYang, Jaeseok
Issue Date
Oct-2021
Publisher
Public Library of Science
Citation
PLoS ONE, v.16, no.10
Indexed
SCIE
SCOPUS
Journal Title
PLoS ONE
Volume
16
Number
10
URI
https://scholarworks.korea.ac.kr/kumedicine/handle/2020.sw.kumedicine/54588
DOI
10.1371/journal.pone.0257981
ISSN
1932-6203
Abstract
Renal functional deterioration is associated with physical and mental burdens for kidney transplant (KT) and chronic kidney disease (CKD) patients. However, the change in health-related quality of life (HRQOL) over time in KT patients compared to that of native CKD patients has not been evaluated. We addressed this issue using KT patients registered in the KNOW-KT cohort study and patients at CKD stage 1-3 registered in the KNOW-CKD cohort study. HRQOL scores were assessed using the Kidney Disease Quality of Life Short Form at baseline, 2-, and 4-years follow-up in 842 KT patients and at baseline and 5-year follow-up in 1,355 CKD patients. SF-36 scores declined at the 4-year follow-up, whereas CKD-targeted scores showed no change in the KT group. In contrast, CKD-targeted scores as well as SF-36 scores were decreased at the 5-year follow-up in CKD patients. When prognostic factors were analyzed for longitudinal HRQOL data over time, renal functions, diabetes, cardiovascular and cerebrovascular diseases, hemoglobin level, marital status, income, employment, and health care were significant prognostic factors. Furthermore, KT was an independent prognostic factor for better HRQOL. These results highlight that KT can offer a better HRQOL than that of CKD patients, even when renal function is similar.</p>
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Kim, Myung Gyu
Anam Hospital (Department of Nephrology and Hypertension, Anam Hospital)
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