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Diagnosis of liver cirrhosis

Authors
Seo Y.S.
Issue Date
Jul-2017
Publisher
Korean Medical Association
Keywords
Liver biopsy; Liver cirrhosis; Shear wave
Citation
Journal of the Korean Medical Association, v.60, no.7, pp.561 - 567
Indexed
SCOPUS
KCI
Journal Title
Journal of the Korean Medical Association
Volume
60
Number
7
Start Page
561
End Page
567
URI
https://scholarworks.korea.ac.kr/kumedicine/handle/2020.sw.kumedicine/5560
DOI
10.5124/jkma.2017.60.7.561
ISSN
1975-8456
Abstract
Liver cirrhosis results from chronic liver injury that leads to necroinflammation and fibrosis. The development of liver cirrhosis is significantly associated with increased morbidity and mortality. Liver biopsy has been considered to be the gold standard for the diagnosis of liver cirrhosis, which is characterized by diffuse fibrosis and the development of regenerating nodules. However, liver biopsy is invasive and has some drawbacks, such as sampling error and intraobserver and interobserver variability in the assessment of fibrosis stages. Recently, various non-invasive tests such as serum markers, radiologic tests, and elastography have been investigated to overcome the limitations of liver biopsy. This review will focus on the use of these non-invasive tests for diagnosing liver cirrhosis. © Korean Medical Association.
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Seo, Yeon Seok
Anam Hospital (Department of Gastroenterology and Hepatology, Anam Hospital)
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