Molecular testing of lymphoproliferative disorders: Current status and perspectivesopen access
- Authors
- Jeon Y.K.; Yoon S.O.; Paik J.H.; Kim Y.A.; Shin B.K.; Kim H.-J.; Cha H.J.; Kim J.E.; Huh J.; Ko Y.-H.; The Hematopathology Study Group of the Korean Society of Pathologists; The Molecular Pathology Study Group of Korean Society of Pathologists
- Issue Date
- 2017
- Publisher
- Seoul National University
- Keywords
- Clonality test; Fluorescence; Gene translocation; In situ hybridization; Lymphoproliferative disorders; Malignant lymphoma; Molecular; Molecular diagnostics; Next-generation sequencing; Pathology
- Citation
- Journal of Pathology and Translational Medicine, v.51, no.3, pp 224 - 241
- Pages
- 18
- Indexed
- SCOPUS
ESCI
KCI
- Journal Title
- Journal of Pathology and Translational Medicine
- Volume
- 51
- Number
- 3
- Start Page
- 224
- End Page
- 241
- URI
- https://scholarworks.korea.ac.kr/kumedicine/handle/2020.sw.kumedicine/5597
- DOI
- 10.4132/jptm.2017.04.09
- ISSN
- 2383-7837
2383-7845
- Abstract
- Molecular pathologic testing plays an important role for the diagnosis, prognostication and decision of treatment strategy in lymphoproliferative disease. Here, we briefly review the molecular tests currently used for lymphoproliferative disease and those which will be implicated in clinical practice in the near future. Specifically, this guideline addresses the clonality test for B- and T-cell proliferative lesions, molecular cytogenetic tests for malignant lymphoma, determination of cellof- origin in diffuse large B-cell lymphoma, and molecular genetic alterations incorporated in the 2016 revision of the World Health Organization classification of lymphoid neoplasms. Finally, a new perspective on the next-generation sequencing for diagnostic, prognostic, and therapeutic purpose in malignant lymphoma will be summarized. © 2017 The Korean Society of Pathologists/The Korean Society for Cytopathology.
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- Appears in
Collections - 2. Clinical Science > Department of Pathology > 1. Journal Articles
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