Detailed Information

Cited 20 time in webofscience Cited 23 time in scopus
Metadata Downloads

Clinical Characteristics and Treatment Outcomes of Cryptogenic Multifocal Ulcerous Stenosing Enteritis in Korea

Authors
Chung, Sook HeePark, Sang UnCheon, Jae HeeKim, Eun RanByeon, Jeong-SikYe, Byong DukKeum, BoraShim, Ki-NamJung, Sung-AeKim, Jin-OhJeon, Seong RanSong, Hyun JooMoon, Jeong SeopChang, Dong Kyung
Issue Date
Sep-2015
Publisher
SPRINGER
Keywords
Cryptogenic multifocal ulcerous stenosing enteritis; Diagnosis; Characteristics; Treatment outcome
Citation
DIGESTIVE DISEASES AND SCIENCES, v.60, no.9, pp.2740 - 2745
Indexed
SCIE
SCOPUS
Journal Title
DIGESTIVE DISEASES AND SCIENCES
Volume
60
Number
9
Start Page
2740
End Page
2745
URI
https://scholarworks.korea.ac.kr/kumedicine/handle/2020.sw.kumedicine/7592
DOI
10.1007/s10620-015-3595-y
ISSN
0163-2116
Abstract
Background Cryptogenic multifocal ulcerous stenosing enteritis (CMUSE) is a rare disease that is characterized by multiple, recurring small intestinal ulcers with stenosis of unknown causes. The aim of this study was to investigate the clinical characteristics and the treatment outcomes of patients with CMUSE in Korea. Methods We performed a multicenter study to retrospectively analyze clinical data from 20 patients who suffered from CMUSE between 1984 and 2012. Their clinical characteristics and long-term disease courses were investigated. Results The most common initial symptom of CMUSE was abdominal pain (14/20, 70 %). Small bowel series (13/20, 65 %), double-balloon enteroscopy (12/20, 60 %), CT enterography (12/20, 60 %), and capsule endoscopy (10/20, 50 %) were used to diagnose CMUSE. The strictures of the patients were located in the jejunum (5/20, 25 %), ileum (7/20, 35 %), and both jejunum and ileum (6/20, 30 %). The number of patients in a state of remission, persistent disease, and relapse at the end of follow-up were 13/20 (65 %), 2/20 (10 %), and 5/20 (25 %), respectively. The median relapse-free survival was of 67.1 months. Seventy-five percent relapse-free survivals for female and male patients were 93 and 9 months, respectively (P = 0.031). Conclusion CMUSE is difficult to diagnose and is an easily relapsing disease. Female patients might have a better prognosis than male patients in terms of the relapse-free time.
Files in This Item
There are no files associated with this item.
Appears in
Collections
2. Clinical Science > Department of Gastroenterology and Hepatology > 1. Journal Articles

qrcode

Items in ScholarWorks are protected by copyright, with all rights reserved, unless otherwise indicated.

Related Researcher

Researcher Keum, Bora photo

Keum, Bora
Anam Hospital (Department of Gastroenterology and Hepatology, Anam Hospital)
Read more

Altmetrics

Total Views & Downloads

BROWSE