Incidence of and Risk Factors for Alzheimer's Disease and Mild Cognitive Impairment in Korean Elderly
- Bae, Jong Bin; Kim, You Joung; Han, Ji Won; Kim, Tae Hui; Park, Joon Hyuk; Lee, Seok Bum; Lee, Jung Jae; Jeong, Hyun Ghang; Kim, Jeong Lan; Jhoo, Jin Hyeong; Yoon, Jong Chul; Kim, Ki Woong
- Issue Date
- Alzheimer' s disease; Mild cognitive impairment; Epidemiology; Incidence; Risk factors; Korea
- DEMENTIA AND GERIATRIC COGNITIVE DISORDERS, v.39, no.1-2, pp.105 - 115
- Journal Title
- DEMENTIA AND GERIATRIC COGNITIVE DISORDERS
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- End Page
- Background/Aims: Knowledge of incidence rates and risk factors is essential for the development of strategies to treat patients with Alzheimer's disease (AD) and mild cognitive impairment (MCI). Methods: A subpopulation of the Nationwide Survey on Dementia Epidemiology (460 Korean subjects aged years from 2 rural and 2 urban districts) was followed up for 3.5 years. The age-specific incidence was estimated and risk factors were identified. Results: The age-standardized incidence of AD and MCI was 7.9 and 28.1 cases per 1,000 person-years, respectively. MCI was associated with a 6-fold increased risk of AD. Depression was a risk factor for AD with MCI. Age, lack of formal education, illiteracy, rural residence, and marital status were associated with the risk of AD. Conclusion: Strategies to control modifiable risk factors should be implemented to decrease the incidence of AD. (C) 20140, Karger AG, Basel.
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- 2. Clinical Science > Department of Psychiatry > 1. Journal Articles
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