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비소세포폐암의 표적 치료Targeted Therapy for Non-Small Cell Lung Cancer
- Other Titles
- Targeted Therapy for Non-Small Cell Lung Cancer
- Issue Date
- Apr-2020
- Publisher
- 대한내과학회
- Keywords
- Non-small cell lung cancer; Molecular targeted therapy; Biomarkers; 비소세포폐암; 표적 치료; 바이오마커
- Citation
- 대한내과학회지, v.95, no.2
- Indexed
- KCI
- Journal Title
- 대한내과학회지
- Volume
- 95
- Number
- 2
- ISSN
- 1738-9364
2289-0769
- Abstract
- [한국어 초록 없음]
Treatment of progressive non-small cell lung cancer (NSCLC) has advanced remarkably, due in part to the development of targeted therapies. Several gene alterations, including EGFR, ALK, ROS1, and BRAF, play important roles in carcinogenesis. Therefore, many targeted agents focusing these gene alterations have been developed and proving their therapeutic efficacies in many clinical trials. Now we should test these gene mutations and should apply treatments individually and properly to ensure the maximal survival benefit of each patient. In this review, we summarize the target genes and respective therapeutic agents in NSCLC.
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Related Researcher
- Kim, Jung Sun
- Ansan Hospital (Department of Medical Oncology and Hematology, Ansan Hospital)