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Cited 2 time in webofscience Cited 3 time in scopus
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Balanced approach can help initial outcomes: analysis of initial 50 cases of a new liver transplantation program in East Asia

Authors
Kim, Dong-SikYu, Young-DongJung, Sung-WonYang, Kyung-SookSeo, Yeon-SeokUm, Soon-HoSuh, Sung-Ock
Issue Date
Jul-2014
Publisher
대한외과학회
Keywords
Liver transplantation; Donor selection; Liver transplantation program; Outcome; Survival
Citation
Annals of Surgical Treatment and Research, v.87, no.1, pp.22 - 27
Indexed
SCIE
SCOPUS
KCI
Journal Title
Annals of Surgical Treatment and Research
Volume
87
Number
1
Start Page
22
End Page
27
URI
https://scholarworks.korea.ac.kr/kumedicine/handle/2020.sw.kumedicine/9162
DOI
10.4174/astr.2014.87.1.22
ISSN
2288-6575
Abstract
Purpose To evaluate patient triage pattern and outcomes according to types of liver transplantation as part of a new liver transplant program developed in an East Asian country with a limited number of deceased donors. Methods Medical records of initial 50 liver transplantations were reviewed retrospectively. Results Twenty-nine patients underwent deceased donor liver transplantation (DDLT) and 21 patients underwent living donor liver transplantation (LDLT). Mean model for end-stage liver disease scores of recipients of DDLT and LDLT were 24.9 ± 11.6 and 13.1 ± 5.4, respectively (P < 0.0001). Twenty-eight patients had HCCs and 17 of them (60.7%) underwent LDLT, which was 80.9% of LDLTs. There were 2 cases of perioperative mortality; each was from DDLT and LDLT, respectively. Median follow-up was 18 months. Overall patient and graft survival rates at 6 months, 1 and 2 years were 95.7%, 93.4%, and 89.8%, respectively. There was no significant difference in survival between DDLT and LDLT. Overall recurrence-free survival rates of hepatocellular carcinoma (HCC) patients at 6 month, 1, and 2 years were 96.3%, 96.3%, and 90.3%, respectively. There was no significant difference in recurrence-free survival between DDLT and LDLT. Conclusion As a new liver transplant program with limited resource and waiting list, patients with critical condition could undergo DDLT whereas relatively stable patients with HCCs were mostly directed to LDLT. We recommend a balanced approach between DDLT and LDLT for initiating liver transplant programs.
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2. Clinical Science > Department of Gastroenterology and Hepatology > 1. Journal Articles
5. Others > Medical Science Research Management Center > 1. Journal Articles
2. Clinical Science > Department of Hepato-Biliary-Pancreatic Surgery > 1. Journal Articles

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Seo, Yeon Seok
Anam Hospital (Department of Gastroenterology and Hepatology, Anam Hospital)
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