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Cited 20 time in webofscience Cited 20 time in scopus
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A randomized, endoscopist-blinded, prospective trial to compare the preference and efficacy of four bowel-cleansing regimens for colonoscopy

Authors
Kim, Eun SunLee, Woo JinJeen, Yoon TaeChoi, Hyuk SoonKeum, BoraSeo, Yeon SeokChun, Hoon JaiLee, Hong SikUm, Soon HoKim, Chang DuckRyu, Ho Sang
Issue Date
Jul-2014
Publisher
INFORMA HEALTHCARE
Keywords
colon bowel preparation; high-fiber diet; sodium picosulfate with magnesium citrate
Citation
SCANDINAVIAN JOURNAL OF GASTROENTEROLOGY, v.49, no.7, pp 871 - 877
Pages
7
Indexed
SCI
SCIE
SCOPUS
Journal Title
SCANDINAVIAN JOURNAL OF GASTROENTEROLOGY
Volume
49
Number
7
Start Page
871
End Page
877
URI
https://scholarworks.korea.ac.kr/kumedicine/handle/2020.sw.kumedicine/9169
DOI
10.3109/00365521.2014.910543
ISSN
0036-5521
1502-7708
Abstract
Objectives. The superiority of conventional polyethylene glycol (PEG) solution over sodium picosulfate with magnesium citrate (SPMC) for bowel preparation remains controversial. Therefore, this study compared the efficacy, safety, and tolerability of different regimens of SPMC and PEG solution in Koreans, who consume a traditional high-fiber diet. Materials and methods. A total of 200 outpatients undergoing elective colonoscopy were randomized into four groups receiving different bowel-preparation regimens in a prospective study: 4 L PEG in the morning on the day of colonoscopy, two 2 L split doses of PEG, split doses of 2 SPMC sachets, and split doses of 3 SPMC sachets. Bowel cleansing efficacy was assessed based on the Ottawa bowel preparation scale and the Aronchick scale by endoscopists blinded to treatment, and patients filled out a questionnaire to determine satisfaction. Results. There was no difference among groups with respect to bowel cleansing grade (Ottawa scale, p = 0.314). Patients in the SPMC groups were less likely to have abdominal fullness, pain, nausea, or vomiting than patients in the PEG groups (p < 0.05). Patients reported SPMC was more palatable than PEG. There were no significant differences among groups with respect to polyp detection rate. Conclusion. SPMC is as effective as conventional high-volume PEG-electrolyte solution in Korean patients. SPMC groups reported superior palatability and tolerability compared to PEG groups.
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5. Others > Others(Medicine) > 1. Journal Articles
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Choi, Hyuk Soon
Anam Hospital (Department of Gastroenterology and Hepatology, Anam Hospital)
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