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Cited 19 time in webofscience Cited 21 time in scopus
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Portal Hypertensive Enteropathy Diagnosed by Capsule Endoscopy in Cirrhotic Patients: A Nationwide Multicenter Study

Authors
Jeon, Seong RanKim, Jin-OhKim, Ji-BeomYe, Byong DukChang, Dong KyungShim, Ki-NamCheung, Dae YoungKim, Jin SooChoi, Myung GyuSong, Hyun JooLim, Yun JeongPark, Soo JungKim, Ji HyunMoon, Jeong SeopJeen, Yoon Tae
Issue Date
May-2014
Publisher
SPRINGER
Keywords
Capsule endoscopy; Enteropathy; Portal hypertension; Liver cirrhosis
Citation
DIGESTIVE DISEASES AND SCIENCES, v.59, no.5, pp.1036 - 1041
Indexed
SCIE
SCOPUS
Journal Title
DIGESTIVE DISEASES AND SCIENCES
Volume
59
Number
5
Start Page
1036
End Page
1041
URI
https://scholarworks.korea.ac.kr/kumedicine/handle/2020.sw.kumedicine/9367
DOI
10.1007/s10620-014-3036-3
ISSN
0163-2116
Abstract
Due to the limited data on portal hypertensive enteropathy (PHE), the prevalence of and clinical factors related to PHE remain unclear. This study determined the prevalence of PHE using capsule endoscopy (CE) and PHE-related clinical factors. This was a retrospective multicenter study using the Capsule Endoscopy Nationwide Database Registry. From 2,879 cases that underwent CE, 45 cirrhosis patients with portal hypertension (PH) were enrolled and divided into PHE (n = 18) and non-PHE (n = 27) groups. From computed tomography (CT) images, six secondary changes due to PH were scored to give a total CT score of 0-6. The main outcome variable was the prevalence of PHE and PHE-related clinical factors. The prevalence of PHE was 40 %. Comparing the PHE and non-PHE groups, the most common findings were angiodysplasias in 55.7 % (vs. 7.4 %, p = 0.001) and varices in 38.9 % (vs. 0 %, p = 0.001). Active bleeding was observed in 16.6 and 3.7 %, respectively, but this difference was not significant. In the univariate analysis, Child-Turcotte-Pugh class C (p = 0.002) and a high CT score (a parts per thousand yen3 vs. < 3, p = 0.004) were significantly associated with PHE. However, only a high CT score was significant in the multivariate analysis (odds ratio 11.19; 95 % confidence interval, 1.59-infinity; p = 0.040). The prevalence of PHE was 40 %, and it might be more prevalent in cirrhosis patients with PH who have a high CT score. CE is a useful diagnostic tool for evaluating PHE in cirrhosis patients with PH.
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Jeen, Yoon Tae
Anam Hospital (Department of Gastroenterology and Hepatology, Anam Hospital)
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