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Efficacy of Helicobacter pylori eradication for the prevention of metachronous gastric cancer after endoscopic resection for early gastric canceropen access

Authors
Jang, Jae YoungChun, Hoon Jai
Issue Date
21-Mar-2014
Publisher
BAISHIDENG PUBL GRP CO LTD
Keywords
Helicobacter pylori; Gastric cancer; Endoscopic resection; Metachronous cancer
Citation
WORLD JOURNAL OF GASTROENTEROLOGY, v.20, no.11, pp.2760 - 2764
Indexed
SCIE
SCOPUS
Journal Title
WORLD JOURNAL OF GASTROENTEROLOGY
Volume
20
Number
11
Start Page
2760
End Page
2764
URI
https://scholarworks.korea.ac.kr/kumedicine/handle/2020.sw.kumedicine/9485
DOI
10.3748/wjg.v20.i11.2760
ISSN
1007-9327
Abstract
Helicobacter pylori (H.pylori) plays an important role in gastric carcinogenesis, as the majority of gastric cancers develop from H. pylori-infected gastric mucosa. The rate of early gastric cancer diagnosis has increased in Japan and Korea, where H. pylori infection and gastric cancer are highly prevalent. Early intestinal-type gastric cancer without concomitant lymph node metastasis is usually treated by endoscopic resection. Secondary metachronous gastric cancers often develop because atrophic mucosa left untreated after endoscopic treatment confers a high risk of gastric cancer. The efficacy of H. pylori eradication for the prevention of metachronous gastric cancer remains controversial. However, in patients who undergo endoscopic resection of early gastric cancer, H. pylori eradication is recommended to suppress or delay metachronous gastric cancer. Careful and regularly scheduled endoscopy should be performed to detect minute meta-chronous gastric cancer after endoscopic resection. (c) 2014 Baishideng Publishing Group Co., Limited. All rights reserved.
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Chun, Hoon Jai
Anam Hospital (Department of Gastroenterology and Hepatology, Anam Hospital)
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