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Comparison between use of fentanyl and rocuronium on outpatient undergoing ultra-short duration gynecologic surgery: a randomized, double-blind, controlled trial

Authors
Choi, Eun-SuLee, Kuen SuKang, Da SomChoi, Yoon JiMin, Too JaeLee, Yoon SookKim, Jae HwanMin, Kyung-JinKim, Woon Young
Issue Date
Apr-2022
Publisher
S O G Canada Inc.
Keywords
Ambulatory anesthesia; Fentanyl; Gynecology surgery; Rocuronium
Citation
Clinical and Experimental Obstetrics and Gynecology, v.49, no.4
Indexed
SCIE
SCOPUS
Journal Title
Clinical and Experimental Obstetrics and Gynecology
Volume
49
Number
4
URI
https://scholarworks.korea.ac.kr/kumedicine/handle/2021.sw.kumedicine/60944
DOI
10.31083/j.ceog4904098
ISSN
0390-6663
Abstract
Background: There has been a steady increase in outpatient-based ultra-short duration gynecology surgeries. However, there are no detailed studies on anesthesia regimens for these surgeries. The aim of this study was to compare the effects of low-dose rocuronium and fentanyl single bolus for their suitability with these patients. Methods: A total of 60 patients were randomly divided into three groups: a control group (group C, n = 20) that received 3 mL of normal saline: a fentanyl group (group F, n = 19) that received 1 mcg/kg of fentanyl; and a low-dose rocuronium group (group R, n = 20) that received 0.3 mg/kg of rocuronium. We collected hemodynamic data during anesthetic induction and the intraoperative period. We also investigated supraglottic airway (SGA) insertion condition, patient's gross movements, and surgeon's satisfaction. In addition, we evaluated the incidence of postoperative nausea and vomiting, pruritus, first voiding time and discharge time from the postanesthetic care unit. Results: Systolic, diastolic, and mean blood pressure were significantly lower in group F after SGA insertion (p = 0.031, p = 0.046 and p = 0.048). SGA insertion conditions scores were significantly worse in group C than in group F and group R for total score (p < 0.001). Also, the number of patient movements during surgery and the number of rescue fentanyl injections were significantly higher in group C than group F and group R (p = 0.005 and p < 0.001). Conclusion: Fentanyl administration at 1 mcg/kg has advantages compared with rocuronium and is a more suitable single agent regimen for outpatient-based ultra-short duration gynecology surgeries.
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2. Clinical Science > Department of Obstetrics and Gynecology > 1. Journal Articles
2. Clinical Science > Department of Anesthesiology and Pain Medicine > 1. Journal Articles

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Lee, Yoon Sook
Ansan Hospital (Department of Anesthesiology and Pain Medicine, Ansan Hospital)
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