암 환자의 가임력 보존open accessFertility preservation for patients with cancer
- Other Titles
- Fertility preservation for patients with cancer
- Authors
- 이상훈; 김탁
- Issue Date
- Jun-2022
- Publisher
- 대한의사협회
- Keywords
- Fertility preservation; Ovary; Cryopreservation; Tissue transplantation; 가임력 보존; 난소종양; 냉동 보존; 조직 이식
- Citation
- Journal of the Korean Medical Association, v.65, no.6, pp 329 - 337
- Pages
- 9
- Indexed
- SCOPUS
ESCI
KCI
- Journal Title
- Journal of the Korean Medical Association
- Volume
- 65
- Number
- 6
- Start Page
- 329
- End Page
- 337
- URI
- https://scholarworks.korea.ac.kr/kumedicine/handle/2021.sw.kumedicine/61236
- DOI
- 10.5124/jkma.2022.65.6.329
- ISSN
- 1975-8456
2093-5951
- Abstract
- [한국어 초록 없음]
Background: The survival rate of cancer patients is increasing owing to the early diagnosis and treatment methods. Radiotherapy and chemotherapy may cause serious complications, such as ovarian failure and infertility. In particular, preservation of fertility in women of reproductive age with cancer could improve their quality of life as well as reduce social and psychological pain.
Current Concepts: Embryo or oocyte cryopreservation is a method of fertility preservation; however, it cannot be utilized by all women with cancer because of the complications of the condition and treatment method. Ovarian tissue cryopreservation and transplantation enables fertility preservation in those needing immediate cancer treatment, such as chemotherapy or radiotherapy, or those unqualified for ovarian stimulation. A recent review reported that frozen-thawed ovarian transplantation led to approximately 130 live births with a conception rate of approximately 30%. Endocrine function recovery occurred in 92.9% of the patients between 3.5 and 6.5 months after transplantation.
Discussion and Conclusion: In this study, we introduced various methods and strategies for improving the outcomes of ovarian tissue cryopreservation and transplantation. These results could serve as a reference for patients and clinicians to choose the best options for fertility preservation based on the patient’s current situation and condition.
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Collections - 2. Clinical Science > Department of Obstetrics and Gynecology > 1. Journal Articles
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