Performance Evaluation of STANDARD Q COVID/FLU Ag Combo for Detection of SARS-CoV-2 and Influenza A/Bopen access
- Authors
- Widyasari, Kristin; Kim, Soomin; Kim, Sunjoo; Lim, Chae Seung
- Issue Date
- Jan-2023
- Publisher
- MDPI AG
- Keywords
- rapid antigen test; SARS-CoV-2; influenza A; influenza B; point-of-care
- Citation
- Diagnostics, v.13, no.1
- Indexed
- SCIE
SCOPUS
- Journal Title
- Diagnostics
- Volume
- 13
- Number
- 1
- URI
- https://scholarworks.korea.ac.kr/kumedicine/handle/2021.sw.kumedicine/62309
- DOI
- 10.3390/diagnostics13010032
- ISSN
- 2075-4418
- Abstract
- We evaluated the performance of the STANDARD Q COVID/FLU Ag Combo test (Q Ag combo test) for the detection of SARS-CoV-2, influenza A, and influenza B using a single point-of-care device compared with real-time PCR. A total of 408 individuals, 55 positives with SARS-CoV-2, 90 with influenza A, 68 with influenza B, and 195 negatives for all viruses, participated. The Q Ag combo test demonstrated a high level of sensitivity of 92.73% and a specificity of 99.49% for the detection of SARS-CoV-2. When the number of days from symptom onset (DSO) was restricted to 0 < DSO <= 6, the sensitivity of the Q Ag combo test to detect SARS-CoV-2 was 100%, and when the Ct value of RdRp was <= 20, the sensitivity to detect SARS-CoV-2 was 93.10%. The Q Ag combo test results also demonstrated a sensitivity of 92.22% and a specificity of 100% for influenza A, a sensitivity of 91.18%, and a specificity of 99.49% for influenza B. The agreement analysis of the Q Ag combo test with the RT-PCR results demonstrated excellent outcomes, making it useful and efficient for the detection of SARS-CoV-2, influenza A, and influenza B.
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- Appears in
Collections - 2. Clinical Science > Department of Laboratory Medicine > 1. Journal Articles
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