Clinical Efficacy and Safety of Endoscopic Treatment of Gastrointestinal Stromal Tumors in the StomachClinical Efficacy and Safety of Endoscopic Treatment of Gastrointestinal Stromal Tumors in the Stomach
- Other Titles
- Clinical Efficacy and Safety of Endoscopic Treatment of Gastrointestinal Stromal Tumors in the Stomach
- Authors
- Joo, Moon Kyung; Park, Jong-Jae; Lee, Yeon Ho; Lee, Beom Jae; Kim, Seong Min; Kim, Won Shik; Yoo, Ah Young; Chun, Hoon Jai; Lee, Sang Woo
- Issue Date
- Feb-2023
- Publisher
- 거트앤리버 발행위원회
- Keywords
- Gastrointestinal stromal tumors; Endoscopy; Recurrence
- Citation
- Gut and Liver, v.17, no.2, pp 217 - 225
- Pages
- 9
- Indexed
- SCIE
SCOPUS
KCI
- Journal Title
- Gut and Liver
- Volume
- 17
- Number
- 2
- Start Page
- 217
- End Page
- 225
- URI
- https://scholarworks.korea.ac.kr/kumedicine/handle/2021.sw.kumedicine/62740
- DOI
- 10.5009/gnl210454
- ISSN
- 1976-2283
2005-1212
- Abstract
- Background/Aims
Gastrointestinal stromal tumors (GISTs) are the most common mesenchymal tumors in the stomach. We evaluated the clinical outcomes of endoscopic treatment for gastric GISTs.
Methods
This is a single center, retrospective study that enrolled 135 cases of gastric subepithelial tumors (SETs) resected by endoscopic procedures and confirmed as GISTs by histopathology from March 2005 to July 2019. The immediate and long-term clinical outcomes were analyzed retrospectively.
Results
The mean patient age was 57.9 years, and the mean tumor size was 2.1 cm. Of the tumors, 43.0% were located in the body, followed by the fundus (26.7%) and cardia (17.0%). Most tumors (85.2%) were resected by endoscopic submucosal dissection, followed by endoscopic mucosal resection (6.7%), submucosal tunneling endoscopic resection (5.9%), and endoscopic full-thickness resection (2.2%). Macroperforation occurred in 4.4% and microperforation in 6.7% of the cases. The R0 resection rate was 15.6%. However, the rate of complete resection by the endoscopic view was 90.4%, of which 54.8% of cases were in the very-low-risk group, followed by the low-risk group (28.1%), intermediate-risk group (11.9%), and high-risk group (5.2%). During 36.5 months of follow-up, recurrence was found in four (3.4%) of the 118 patients who were monitored for more than 6 months (low-risk group, 1/37 [2.7%]; intermediate-risk group, 2/11 [18.2%]; high-risk group, 1/6 [16.7%]).
Conclusions
Endoscopic treatment of a GIST appears to be a feasible procedure in selected cases. However, additional surgery should be considered if the pathologic results correspond to intermediate- or high-risk groups.
- Files in This Item
- There are no files associated with this item.
- Appears in
Collections - 2. Clinical Science > Department of Gastroenterology and Hepatology > 1. Journal Articles
Items in ScholarWorks are protected by copyright, with all rights reserved, unless otherwise indicated.