Core indicators related to the elimination of hepatitis B and C virus infection in South Korea: A nationwide studyopen access
- Authors
- Hun, Chang; Hyeon, Gwang; Choi, Hwa Young; Han, Sojung; Jang, Eun Sun; Chon, Young Eun; Chang, Young; Kim, Kyung-Ah; Kim, Do Young; Yim, Hyung Joon; Kim, Hye-Li; Jeong, Sook-Hyang; Kim, In Hee
- Issue Date
- Jul-2023
- Publisher
- 대한간학회
- Keywords
- Hepatitis B; Hepatitis C; Incidence; Diagnostic screening programs; Mortality
- Citation
- Clinical and Molecular Hepatology, v.29, no.3, pp 779 - 793
- Pages
- 15
- Indexed
- SCIE
SCOPUS
KCI
- Journal Title
- Clinical and Molecular Hepatology
- Volume
- 29
- Number
- 3
- Start Page
- 779
- End Page
- 793
- URI
- https://scholarworks.korea.ac.kr/kumedicine/handle/2021.sw.kumedicine/63983
- DOI
- 10.3350/cmh.2023.0110
- ISSN
- 2287-2728
2287-285X
- Abstract
- Background/Aims: To eliminate hepatitis B virus (HBV) and hepatitis C virus (HCV) according to the World Health Orga-nization (WHO) criteria in 2021, this study investigated the national core indicators representing the current status of viral hepatitis B and C in South Korea. Methods: We analyzed the incidence, linkage-to-care, treatment, and mortality rates of HBV and HCV infection using the integrated nationwide big data of South Korea. Results: According to data from 2018-2020, the incidence of acute HBV infection in South Korea was 0.71 cases per 100,000 population; tthe linkage-to-care rate was only 39.4%. Among those who need hepatitis B treatment, the treat-ment rate was 67.3%, which was less than 80% reported in the WHO program index. The annual liver-related mortality due to HBV was 18.85 cases per 100,000 population, exceeding the WHO target of four; the most frequent cause of death was liver cancer (54.1%). The annual incidence of newly diagnosed HCV infection was 11.9 cases per 100,000 population, which was higher than the WHO impact target of five. Among HCV-infected patients, the linkage-to-care rate was 65.5% while the treatment rate was 56.8%, which were below the targets of 90% and 80%, respectively. The liver-related annual mortality rate due to HCV infection was 2.02 cases per 100,000 population. Conclusions: Many of the current indicators identified in the Korean population did not satisfy the WHO criteria for validation of viral hepatitis elimination. Hence, a comprehensive national strategy should be urgently developed with continuous monitoring of the targets in South Korea. (Clin Mol Hepatol 2023;29:779-793)
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Collections - 2. Clinical Science > Department of Gastroenterology and Hepatology > 1. Journal Articles
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