Molecular Mechanisms Associated with Aging Kidneys and Future Perspectivesopen access
- Authors
- Jo, Min-Jee; Lee, Joo-Kyung; Kim, Ji-Eun; Ko, Gang-Jee
- Issue Date
- Dec-2023
- Publisher
- Multidisciplinary Digital Publishing Institute (MDPI)
- Keywords
- aging kidney; glomerulosclerosis; inflammation; cell cycle; oxidative stress
- Citation
- International Journal of Molecular Sciences, v.24, no.23
- Indexed
- SCIE
SCOPUS
- Journal Title
- International Journal of Molecular Sciences
- Volume
- 24
- Number
- 23
- URI
- https://scholarworks.korea.ac.kr/kumedicine/handle/2021.sw.kumedicine/64938
- DOI
- 10.3390/ijms242316912
- ISSN
- 1661-6596
1422-0067
- Abstract
- The rapid growth of the elderly population is making the need for extensive and advanced information about age-related organ dysfunction a crucial research area. The kidney is one of the organs most affected by aging. Aged kidneys undergo functional decline, characterized by a reduction in kidney size, decreased glomerular filtration rate, alterations in renal blood flow, and increased inflammation and fibrosis. This review offers a foundation for understanding the functional and molecular mechanisms of aging kidneys and for selecting identifying appropriate targets for future treatments of age-related kidney issues.
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- Appears in
Collections - 4. Research institute > Institute of Convergence New Drug Development > 1. Journal Articles
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