발효흑마늘 추출물이 흰쥐의 지질대사 및 간기능 개선에 미치는 영향Effects of the Fermented Black Garlic Extract on Lipid Metabolism and Hepatoprotection in Mice
- Other Titles
- Effects of the Fermented Black Garlic Extract on Lipid Metabolism and Hepatoprotection in Mice
- Authors
- 정수연; 이용권; 한경훈; 배송환; 한성희
- Issue Date
- Dec-2019
- Publisher
- 한국식품영양학회
- Keywords
- Key words: fermented black garlic extract; anti-obesity; hepatoprotection; antioxidant activity; S-allyl-L-cysteine
- Citation
- 한국식품영양학회지, v.33, no.1, pp 17 - 26
- Pages
- 10
- Indexed
- KCI
- Journal Title
- 한국식품영양학회지
- Volume
- 33
- Number
- 1
- Start Page
- 17
- End Page
- 26
- URI
- https://scholarworks.korea.ac.kr/kumedicine/handle/2020.sw.kumedicine/52686
- DOI
- 10.9799/ksfan.2020.33.1.017
- ISSN
- 1225-4339
- Abstract
- This study was conducted to evaluate the functionality of fermented black garlic extracts under various conditions. Black garlic powder was prepared by aging for 0~72 hours at 80℃ depending on relative humidity (RH). It showed the highest antioxidant effects among the samples; the total antioxidant activity of black garlic powders at RH 75%, 84%, and 90% for 72 hours was increased 31.9 times, 28.2 times, and 22.6 times compared with that of the fresh garlic powder, respectively. Also, the alliin content was gradually decreased. S-ally-L-cysteine and S-ethyl-cysteine levels were increased; the highest values were 495.9 μg/g and 1,769.7 μg/g after aging for 72 hours at RH 75%. Aspartate transaminase (AST) and alanine transaminase (ALT) levels were increased following high fat diet feeding, but the rise was obviously reduced by administration of black garlic extract. The total cholesterol, LDL/VLDL-cholesterol, and triglyceride contents in serum were significantly lower in methionine and choline deficient (MCD) diet treatment groups than in the positive control group. The concentration was increased following the intake of black garlic and fermented black garlic extracts. Therefore, black garlic extracts could be an ideal material as a dietary supplement in healthy functional foods to improve the effects on fatty liver. Key words: fermented black garlic extract, anti-obesity, hepatoprotection, antioxidant activity, S-allyl-L-cysteine
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Collections - 4. Research institute > Institute of Human Behavior and Genetics > 1. Journal Articles
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