Detailed Information

Cited 0 time in webofscience Cited 0 time in scopus
Metadata Downloads

Is There a Difference in the Incidence of Depression between Radiation and Surgical Treatments in Patients with Prostate Cancer?open access

Authors
Tae, Bum SikAhn, Sun TaeYoo, Jung WanSong, Min SungChoi, HoonBae, Jae HyunPark, Jae Young
Issue Date
Jan-2024
Publisher
대한남성과학회
Keywords
Depression; Prostatic neoplasms; Surgery; Radiotherapy
Citation
The World Journal of Men's Health, v.42, no.1, pp 237 - 244
Pages
8
Indexed
SCIE
KCI
Journal Title
The World Journal of Men's Health
Volume
42
Number
1
Start Page
237
End Page
244
URI
https://scholarworks.korea.ac.kr/kumedicine/handle/2021.sw.kumedicine/65417
DOI
10.5534/wjmh.230119
ISSN
2287-4208
2287-4690
Abstract
Purpose: Patients with cancer have a high risk of depression. However, a few studies have assessed differences in the inci-dence of depression among patients with prostate cancer (PC) based on whether they received radiotherapy (RTx) or surgical treatment.Materials and Methods: We analyzed data from the National Health Insurance Sharing Service database regarding the entire Korean adult population with PC (n=210,924) between 2007 and 2017. The adjusted hazard ratios (HRs) of depression as-sociated with treatment were estimated using propensity score-matched Cox proportional hazards models and Kaplan-Meier survival analyses.Results: Our final cohort comprised 9,456 patients with PC; of which, 8,050 men underwent surgery. During a mean follow-up duration of 7.1 years, 503 (5.3%) patients were newly diagnosed with depression. A significant difference in the incidence of depression was noted between the RTx and surgery groups (RTx vs. surgery: 5.55% vs. 5.28%; p=0.011) in the unmatched cohort. In the matched cohort, older age (>= 70 years, HR: 1.596, p<0.001) and poor Charlson comorbidity index scores (HR: 1.232, p=0.039) were correlated with the risk of depression. In addition, the adjusted HR for depression in the surgery group was 0.843 (p=0.221) compared with that in the RTx group. Kaplan-Meier analyses revealed that no significant difference in the cumulative probability of persistent depression was detected between the RTx and surgery groups in matched cohort (p=0.3386).Conclusions: In this nationwide population-based study, no significant differences in the risk of depression were observed between the surgical and RTx groups.
Files in This Item
There are no files associated with this item.
Appears in
Collections
5. Others > ETC > 1. Journal Articles

qrcode

Items in ScholarWorks are protected by copyright, with all rights reserved, unless otherwise indicated.

Related Researcher

Researcher Tae, Bum Sik photo

Tae, Bum Sik
Ansan Hospital (Department of Urology, Ansan Hospital)
Read more

Altmetrics

Total Views & Downloads

BROWSE